To prevent overtreatment in the future, researchers at The Netherlands Cancer Institute and the VIB-KU Leuven Center for Cancer Biology developed a "living biobank" of DCIS cells to better understand their progression to cancer.įollowing the 'live' process from DCIS to breast cancer Therefore, virtually all women with DCIS are treated preventively through mastectomy or breast-conserving surgery followed by radiation and, in some countries, hormone therapy.Īs a result, tens of thousands of women around the world undergo intensive treatment without any benefit, but suffer the disadvantages.
To this day, however, it is not possible to predict which DCIS will progress to breast cancer and which will not. This is because calcium splashes can be seen on the X-ray of the breast (the mammogram), which may indicate DCIS. In the Netherlands, it is found in about 2,300 women a year, about 80% of them detected at breast cancer screening.
The study was published in Cancer Cell and is part of PRECISION, a major international research project on DCIS.ĭCIS consists of aberrant cells in the milk ducts of the breast.
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